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Altered tau forms characteristic pathogenic inclusions in Alzheimer’s disease and related tauopathies. Although, tau hyperphosphorylation is widely considered to be the major trigger of tau malfunction, tau undergoes several post translational modifications at lysine residues including acetylation, methylation, ubiquitylation, SUMOylation, and glycation. We are only beginning to define the site specific impact of each type […]

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Testimony could raise more questions about the extent of Sessions knowledge about interactions between Trump campaign aides and Russians. Sessions recused himself from overseeing an investigation into the Trump campaign in March after acknowledging two previously undisclosed conversations with former Russian ambassador Sergey Kislyak during the campaign. Since then, Sessions has downplayed his own knowledge […]

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